Endocrine Abstracts

Introduction: Peutz-Jeghers syndrome (PJS) is a rare familial disorder with an incidence of one in 12–30,000 live births characterized by mucocutaneous pigmentation, gastrointestinal and extra gastrointestinal hamartomatous polyps and an increased risk of malignancy.Case presentation: We report a 22-year-old female hypothyroid since age of 4, type 1 diabetic since age of 11, who presented with melaena. Pigmentation of the buccal mucosa, multiple lip...

Introduction: Lipodystrophic syndromes are a heterogeneous group of congenital or acquired disorders characterized by either complete or partial lack of adipose tissue. Other prominent abnormalities of these disorders include Diabetes Mellitus and acanthosis nigricans due to the associated insulin resistance. Liver affection is common due to fatty infiltration of the liver, which can lead to cirrhosis and its complications.Clinical case: A 31 years old s...